Showing posts from May, 2021

Western diet may increase the risk of gut inflammation, infection

  Western diet may increase the risk of gut inflammation, infection Diet rich in sugar, fat damages immune cells in the digestive tracts of mice According to a study from researchers at Washington University School of Medicine in St. Louis and Cleveland Clinic, eating a Western diet impairs the immune system in the gut in ways that could increase the risk of infection and inflammatory bowel disease. In mice and people, the study showed that a diet high in sugar and fat causes damage to Paneth cells, immune cells in the gut that help keep inflammation in check. When Paneth cells aren't functioning properly, the gut immune system is excessively prone to inflammation, putting people at risk of inflammatory bowel disease and undermining effective control of disease-causing microbes. The findings, published May 18 in  Cell Host & Microbe , open up new approaches to regulating gut immunity by restoring normal Paneth cell function. "Inflammatory bowel disease has historically bee

The secret behind maintaining a healthy weight loss

  The secret behind maintaining a healthy weight loss Half of the Danish population have overweight, while 17 percent live with obesity. Worldwide, almost 40 percent are overweight, and 13 percent live with obesity. The condition is associated with an increased risk for early death and sequelae such as Type 2 diabetes, cardiovascular diseases, cancer, and infertility. Weight regain after an initially successful weight loss in people with obesity constitutes an important and unsolved problem. Until now, no well-documented study on which treatment method is best for maintaining a healthy weight loss has been available. Researchers at the University of Copenhagen and Hvidovre Hospital have completed a new, sensational study, which is being published in the world's most quoted medical journal, The  New England Journal of Medicine . By testing four different types of treatment following a diet-induced weight loss, the researchers demonstrate for the first time how people with obesity ca

Colorectal cancer screening to begin at age 45, lowered from 50

  Colorectal cancer screening to begin at age 45, lowered from 50 Prompted by a recent alarming rise in cases of colorectal cancer in people younger than 50, an independent expert panel has recommended that individuals of average risk for the disease begin screening exams at 45 years of age instead of the traditional 50. The guideline changes by the U.S. Preventive Services Task Force (USPSTF), published in the current issue of  JAMA , updates its 2016 recommendations and aligns them with those of the American Cancer Society, which lowered the age for initiation of screening to 45 years in 2018. Colorectal cancer (CRC) is one of the most preventable malignancies, owing to its long natural history of progression and the availability of screening tests that can intercept and detect the disease early. The overall incidence of CRC in individuals 50 years of age and older has declined steadily since the mid-1980s, largely because of increased screening and changing patterns of modifiable ri


  SHORT HIIT WORKOUTS HAVE BEEN SHOWN EFFECTIVE FOR IMPROVING HEALTH High-intensity interval training has become increasingly popular as it's a quick and effective way to improve health. This is all the more important as countries worldwide emerge from lockdowns due to coronavirus and are looking for a quick and easy way to exercise again. Researchers have recently studied whether shorter variations of HIIT, involving as little as 4-min of high-intensity exercise per session (excluding a warm up and cool down), also improve health. A new review paper published in the  Journal of Physiology  collates a decade's worth of research on the topic of this so-called low-volume high HIIT for health. The current World Health Organisation (WHO) physical activity guidelines (150-300 min of moderate activity/week or 75-100min of vigorous activity/week) may be unattainable for a large portion of the population who are time poor due to family or work commitments. This hypothesis is supported