LONGER OVERNIGHT FAST AND EARLY BREAKFAST ARE BETTER FOR WEIGHT LOSS

 

LONGER OVERNIGHT FAST AND EARLY BREAKFAST ARE BETTER FOR WEIGHT LOSS

The study suggests new patterns in the relationship between mealtimes and body weight.

    


To control weight, we must consider what and when we eat. According to a study published in the International Journal of Behavioral Nutrition and Physical Activity, two specific habits are associated with a lower body mass index (BMI) in the long term: keeping a longer overnight fast and eating breakfast early. This research was led by the Barcelona Institute for Global Health (ISGlobal), a center supported by the "la Caixa" Foundation.

The study involved more than 7,000 volunteers aged 40 to 65 from the GCAT | Genomes for Life cohort, a project led by the Germans Trias I Pujol Research Institute (IGTP). In 2018, participants answered questionnaires about their weight, height, eating habits, meal times, other lifestyle habits, and socioeconomic status. In 2023, after five years, more than 3,000 participants made a follow-up visit to the research team, where their measurements were re-recorded and new questionnaires were completed.

Interpretation of results

"Our results, in line with other recent studies, suggest that extending the overnight fast could help maintain a healthy weight if accompanied by an early dinner and breakfast. We think this may be because eating earlier in the day is more aligned with circadian rhythms and allows for better calorie burning and appetite regulation, which can help maintain a healthy weight. However, it is too soon to draw definitive conclusions, so recommendations will have to wait for more robust evidence," explains Luciana Pons-Muzzoa, a researcher at ISGlobal at the time of the study and currently at IESE Business School.

Gender differences

Analysis of the data by gender showed that, compared to men, women generally showed lower BMI, higher adherence to the Mediterranean diet, lower propensity to consume alcohol, poorer mental health, and were more likely to be responsible for household or family supervision.

The team used a statistical technique called 'cluster analysisto group individuals with similar characteristics. From this analysis, the authors were struck by a small group of men whose first meal of the day was after 2:00 PM and who, on average, fasted for 17 hours. Compared to the rest, this group of men tended to have less healthy lifestyles (more likely to smoke, drink alcohol, have less physical activity, and have less adherence to the Mediterranean diet), lower educational attainment and were more likely to be unemployed. These patterns were not observed in any group of women.

On intermittent fasting

"There are different ways of practicing what is known as 'intermittent fasting,' and our study relates to one of them, which is overnight fasting. What we observed in a subgroup of men who do intermittent fasting by skipping breakfast is that this practice has no effect on body weight. Other intervention studies in participants with obesity have shown that this tactic is no more effective than reducing calorie intake in reducing body weight in the long term," says Camille Lassale, ISGlobal researcher and senior co-author of the study.

"Our research is part of an emerging field of research known as 'Chrono nutrition,' which focuses not only on analyzing what we eat but also the times of day and the number of times we eat," says Anna Palomar-Cros, a researcher at ISGlobal at the time of the study and currently at IDIAP Jordi Gol. "At the basis of this research is the knowledge that unusual food intake patterns can conflict with the circadian system, the set of internal clocks that regulate the cycles of night and day and the physiological processes that must accompany them," she adds.

Previous studies

This study provides continuity to a line of research on Chrono nutrition, which has published two other studies with similar results in recent years. In these studies, eating dinner and breakfast early was associated with a respective risk of cardiovascular disease and type 2 diabetes.



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