Fish Oil And Prostate Cancer
A year-long diet high in omega-3s and low in omega-6s, paired with fish oil supplements, may help slow down prostate cancer progression in men who are monitoring their cancer through active surveillance, according to new research published online Dec. 13 in the Journal of Clinical Oncology.
Researchers led by Dr. William J. Aronson at UCLA tracked 100 men with early-stage prostate cancer (grade 1 or 2) who chose active surveillance instead of immediate treatment. The study compared those who followed the special diet and took fish oil capsules (dubbed D + FO) to a control group.
After one year, the D + FO group saw their Ki-67 index—a marker linked to cancer cell growth—drop by about 15% (from 1.34% to 1.14%). In contrast, the control group’s Ki-67 index rose by roughly 24% (from 1.23% to 1.52%). This difference was statistically significant. When it came to other measures like cancer grade, tumor size, Decipher genomic risk score, and PSA levels, there wasn’t much difference between the two groups. Four men in the D + FO group left the study because of side effects from the fish oil.
The authors say these results pave the way for larger phase III trials to see if this diet and supplement combo could benefit more men choosing surveillance over immediate prostate cancer treatment.
It’s worth noting that two authors reported connections to the pharmaceutical industry.
A quick reminder: Statistics from medical studies show general patterns and might not apply to everyone. For decisions about your own health, always talk to your doctor.

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