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INPEFA: MULTI-EFFECT DRUG

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  INPEFA: MULTI-EFFECT DRUG     A groundbreaking diabetes drug is doing more than anyone expected. New research shows it's protecting patients from heart attacks and strokes, marking a significant leap forward in treatment options for those with type 2 diabetes and kidney problems. Sotagliflozin is a drug that works differently from its predecessors. It is a double-action shield: It blocks two proteins (SGLT1 and SGLT2) that manage blood sugar levels, while other similar drugs only target one. This unique approach is turning heads in the medical community. The results of a massive international study by Dr. Deepak Bhatt at Mount Sinai were striking. Over 10,000 patients participated, and those taking sotagliflozin saw their risk of heart attacks, strokes, and related deaths drop by 23 percent. That's nearly a quarter fewer life-threatening events – a difference that could mean thousands of lives saved. "We're seeing something entirely new here," says Dr. Bhatt, wh...

CANCER SCREENINGS: AN ESSENTIAL GUIDE

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CANCER SCREENINGS:  AN ESSENTIAL GUIDE Let's talk about something nobody wants to think about, but everyone needs to know: cancer screenings. Here's the good news: catching cancer early can be the difference between a scary diagnosis and a treatable condition. With doctors expecting about 2 million new cancer cases this year, these screenings aren't just another item on your to-do list - they're your best defense against cancer. Since it's National Cancer Prevention Month, there's no better time to ensure you're on track with your screenings. The experts at Rutgers Cancer Institute and RWJBarnabas Health have put together clear guidelines based on your age and risk factors. Let's break them down. Colorectal Cancer: Yes, It's Time to Start at 45 Think you're too young to worry about colorectal cancer? Think again. Everyone needs to start getting checked at 45, earlier if cancer runs in your family. You've got options here: The gold standard is...

AGING WELL BY WORKING LONGER

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AGING WELL BY WORKING LONGER The traditional image of retirement - trading office chairs for beach chairs at 65 - is becoming a relic of the past. A groundbreaking new poll from the University of Michigan reveals that working later in life might be the secret to staying sharp, healthy, and fulfilled. The findings contradict our assumptions about work and aging. Over two-thirds of Americans report that keeping their careers going has boosted their physical and mental health. Here's where it gets exciting: Those past 65 reap even greater rewards . "We're seeing a complete shift in how we think about work after 65," says Dr. Jeffrey Kullgren, who directed the poll at Michigan's Institute for Healthcare Policy and Innovation. "For many older adults who can still work, it's becoming a powerful tool for maintaining health and mental sharpness." The numbers tell a compelling story. Nearly half of working older adults say their jobs give them a vital sense o...

OZEMPIC: COMBATS ALCOHOL DEPENDENCE

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OZEMPIC: COMBATS ALCOHOL DEPENDENCE   New research brings exciting news for those struggling with alcohol  Dependence: Ozempic, a diabetes and weight-loss medication that's been making headlines, might have another powerful benefit. A groundbreaking study just released in JAMA Psychiatry shows that the popular GLP-1 drug could be a game-changer for people looking to cut back on drinking. And the timing couldn't be better, considering how few effective treatments currently exist for alcohol use disorder. The story behind this discovery is fascinating. It started when doctors noticed something unexpected: their patients taking Ozempic for weight loss or diabetes were spontaneously reporting less interest in alcohol. This real-world observation led researchers at the University of Southern California to dig deeper. Led by Christian Hendershot, director of clinical research at USC's Addiction Research Center, the team designed a clever experiment. They recruited 48 adults who r...

AGING: HOW IT'S MEASURED

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  AGING: HOW IT'S MEASURED Now, science can measure your age with blood tests to help you make health and medical decisions. How old are you? That question may not be as simple as it sounds. Scientists have discovered something fascinating: Two people born on the same day can have bodies that age at different rates. It all comes down to biological age, which measures how well a body functions rather than just how long it's been around. And here's where it gets interesting: Researchers at Penn State have found that how we measure this biological age makes a huge difference. Lead researcher Abner Apsley and his team discovered something crucial that might save you from wasting money on those trendy at-home aging tests. It turns out that when measuring biological age, not all body tissues tell the same story. Those mail-in saliva tests that promise to reveal your "true age"? They might be off by as much as 30 years. The science behind this involves epigenetic clocks,...

OMEGA-3 MAY SLOW AGING

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  OMEGA-3 MAY SLOW AGING Want to turn back the clock? Popping a daily omega-3 supplement might be the best way to find the youth fountain. A groundbreaking study from the University of Zurich revealed something fascinating: taking one gram of omega-3s daily could slow biological aging by up to four months. While four months might not sound like much, this is a significant breakthrough in understanding how we can influence aging. The story begins with the DO-HEALTH study, an ambitious research project that followed over 2,000 people aged 70 and up across Europe. Scientists were interested in more than just how old people's birth certificates said they were—they wanted to know how old their bodies were at a molecular level. To understand this, they used epigenetic clocks. These sophisticated biological timekeepers measure how our DNA changes as we age. They are like high-tech fitness trackers, but instead of counting steps, they count the chemical changes that mark the passage of tim...

YOUR BRAIN ON CANNABIS: IT'S COMPLICATED

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  YOUR BRAIN ON CANNABIS: IT'S COMPLICATED A fascinating study published in JAMA Network Open reveals some surprising insights about how heavy marijuana use affects our mental machinery, especially when it comes to memory. Picture this: researchers at the University of Colorado rounded up over 1,000 young adults, ages 22 to 36, and put their brains to the test. Using sophisticated brain imaging technology, they watched what happened inside the minds of heavy cannabis users, moderate users, and those who'd never touched the stuff. The results? Heavy cannabis users showed noticeably less brain activity during memory-related tasks, particularly in three key brain regions: the anterior insula (think emotional processing), the medial prefrontal cortex (decision-making central), and the dorsolateral prefrontal cortex (the brain's multitasking maestro). Their brains were running on energy-saving mode, but not in a good way. Here's where it gets interesting: recent cannabis use...